His Gonzo days: Crappy camera work, dodgy greenscreen visuals, general anarchy, a crusty old sofa and the biggest bands of the time thrust into DIY madness made this MTV2 format the perfect format for Lowe's boundless enthusiasm yet casual nature to really get to know bands. We'd highly recommend you take the time to Youtube some of it - his Gonzo chats with the likes of Muse, The Libertines, Placebo, Queens Of The Stone Age, Arctic Monkeys, Oasis, Kings Of Leon and Interpol have since going down in history.
The Masterpiece series: A simple but brilliant idea, between 2007 and 2012 Lowe used his prime time Radio One slot to celebrate truly great alternative albums - with the first of his show interviewing bands to talk about the true impact of classic albums, and the second half playing them uncensored in full. As a result, a vast audience got to know and fall in love with works by the likes of Queens Of The Stone Age, Public Enemy, The Strokes, Rage Against The Machine, Radiohead, The Streets, Jay Z, Dizzee Rascal, Beastie Boys and many more.
THAT Kanye West interview: The true unhinged genius of Yeezy is on show in this classic interview from 2013 - in which West confesses to be 'the biggest rock star in the world', admits he's "reached a moment in life where my Truman show boat has hit the wall", and says something about leather jogging pants - with Lowe keeping a bemused cool throughout.
THAT Glastonbury moment: Now now, hear us out - we absolutely love Lauren Laverne and all that she does, but this was classic TV. She's there, doing her charming and informed analysis of the cultural impact of Beyonce's game-changing Glasto headline performance, while Lowe, still in a daze from seeing Queens Of The Stone Age, totally zones out before bursting into an explosion of nervous laughter. The contrast between his indifference in comparison to normal childish glee nearly breaks Twitter, and Jo Wiley is brought in to replace him.
His MTV2 specials: The Gonzo format was given somewhat of a facelift to feature nicer chairs, some classy lighting and giving Lowe the chance to really get under the skin of the acts with lengthy, extended interviews - the career-spanning chats with Oasis and Morrissey being particular highlights.
The Drive re-scoring project: The soundtrack was already a modern classic, which is why you have to admire Lowe's ambition. Love or hate results, it was interesting to see the film inspire bands to create something original, while at the heart of it laid Lowe's main purpose and passion: championing new and alternative music. In doing so, he also gave us some truly cracking tunes from Chvrches, The 1975, BANKS, Foals and more.
But let's not forget his live show: That same enthusiasm and break-neck hip-hop speed that we loved his radio show for translated even better into the live area. Whether collaborating with Mark Ronson or just defying genres at the highest volume into the early hours, Lowe has become a live favourite at festivals, student nights and even proving an awesome support act for everyone from Biffy Clyro and The Weeknd to Muse at their historic Wembley Stadium shows. America is lucky to have him.
Saving Ryan Jarman's life: Yes, without Zane we'd also be without our Ryan from The Cribs too. In a story now ingrained in indie folklore, Jarman was collecting an award on behalf of Franz Ferdinand at the 2006 NME Awards, before jumping onto Kaiser Chiefs' table - cutting himself on broken glass that narrowly escaped his vital organs. He soon discharged himself from hospital to hit an afterparty, where Lowe found him bleeding heavily in a hallway before calling an ambulance.
Being nominated for a Grammy: Zane's also a successful remixer, producer and writer - even nominated for a GRAMMY for his credit on Sam Smith's In The Lonely Hour, which is impressive.
Making the 'Hottest Record In The World' a true badge of honour: Long may it continue.